In vivo imaging device with fiber optic

Overview

An optical detection apparatus for capturing fluorescence signals from deep tissue, aimed at functional brain imaging that can run alongside MRI.

Light is collected through a microstructured fiber built from multiple solid waveguide cores separated by hollow tubes, then imaged onto a silicon photomultiplier array with each beam magnified to roughly one pixel. The design records dynamic signals from many channels at once while preserving single-cell specificity.

Reference

Yu X, Jiang Y, Russell PStJ, Frosz MH, Schlüsener JK. In vivo imaging device with fiber optic. European Patent EP3375367A1, Max Planck Gesellschaft. Filed 2017-03-17, published 2018-09-19. Application No. 17161518.